The present study was conducted to investigate the parasite infestation of Wallago attu and Rita rita during January, 2011 to December, 2012. A total of 11 species of parasites were identified from Wallago attu, with one ectoparasite (Argulus foliaceus) and 10 endo-parasites of which three were trematodes (Isoparorchis hypselobagri, Macrolecithus gotoi, Magnacetabulum trachuri); two nematodes (Contracaecum L larva, Cosmoxynemoids aguirrei); 3 one cestode (Polyoncobothrium polypteri) and four acanthocephalas (Echinorhynchus kushiroense, Pallisentis ophiocephali, Acanthocephalus aculeatus, Pallisentis umbellatus). From Rita rita, a total of 9 species of parasites were recovered and among them, one ecto-parasite (Lernaea cyprinacea) and 8 endo-parasites of which four trematodes (Notoporus leiognathi, Saccacoelium obesum, Sterrhurus musculus, Clinostomum piscidium); one nematode (Ascaroid larva) and three acanthocephalas (Cavisoma magnum, Corynosoma alaskense, Corynosoma strumosum). The prevalence of ecto-parasite was 23.6% in Wallago attu and mean intensity of parasite was 3.11±1.47, while, in Rita rita, 24.8% were infected with a mean intensity of 3.34±1.62. The prevalence of endo-parasites was 34.4% in Wallago attu and mean intensity of parasites was 1.66±0.24, while, in Rita rita, 64.57% with a mean intensity of 2.64±1.12. Most of the parasites were found to favour the intestine of the fishes, except Isoparorchis hypselobagri harboured the swim bladder. The prevalence in Wallago attu was observed higher during winter, while in Rita rita, it was higher in rainy season.