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Year: 2019, Issue: December
Effect of different photoperiods of lung associated cellular immunity of diabetic Albino rat.
Rajesh Kumar Kharwar, Vaishali Singh and Krishna Yadav
LAIS, Photoperiod, Melatonin, Immunity, Diabetes
To study the effect of photoperiod on lung associated cellular immunity in diabetic rats, different photoperiod regimens were used. These were - Long photoperiod (LP; 20L:4D), Short photoperiod (SP; 4L:20D) and natural day length for control group. The cell mediated immunity was evaluated in terms of size of Bronchus Associated Lymphoid Tissue (BALT) and non-BALT nodules and percent stimulation ratio of lung isolated lymphocytes which was supported by peripheral lymphocyte count (percent). Short photoperiod increased bronchusassociated lymphoid tissue (BALT) and non-BALT nodule size, peripheral lymphocyte count and percent stimulation ratio of lymphocytes. LP decreased the above-mentioned immune parameters suggesting that photoperiod might be regulating lung-associated immune system (LAIS) via melatonin during diabetic condition.
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