Black quarter (BQ) is an acute, infectious disease caused by Clostridium chauvoei - a Gram-positive, anaerobic organism. This disease is characterized by inflammation with gaseous oedema of skeletal muscle and severe toxaemia. The present study was conducted on a cow of 6 years old weighing 400 kg presented with BQ to establish new avenues in the field of therapeutic management of BQ in bovines. As the case was presented and diagnosed at an early stage, i.e. 12 hrs within the development of clinical symptoms, antibiotic therapy was found to be effective. The debridement of edematous and putrefied part was done with the help of Hydrogen peroxide (H O ), Magnesium 2 2 Sulphate (MgSo ) and regular dressing for 10th days followed by dressing at regular intervals. The BQ affected wound 4 healed after 3 months of treatment. The present study could be helpful for the field Veterinary Professionals in managing the cases of BQ therapeutically in bovines.