Gallbladder cancer is relatively uncommon but second most cancer caused by bacteria. The link between Salmonella typhi as a carcinogen and the development of cancer in gallbladder has already been established (Scanu et al.,2015 and Jill et al.,2016). This might be a surprising truth for us to learn that the S.typhi after an infection usually persisted in the gallbladder for a longer period of time causing cancer in human. The present paper deals with the study of causes and the consequences of typhoid fever and the production of gallbladder carcinoma in human.