Ethanolic extract of Mesua ferrea (Nagkesar) flower was prepared and it's in vitro phytochemical composition and radical scavenging activity was carried out of different parameters. Saponin, flavanoid, terpenoid and tannin are found as major phytoconstituents in flower ethanolic extract of Mesua ferrea flower. Study also reflected radical scavenging activity in in vitro assays. It showed a concentration dependent increase in radical scavenging activity. Outcome of the present study suggested assessing the Mesua ferrea at its in vivo level to develop it a good phytotherapeutic system