For fulfilling the increasing demand of human need establishment of many industries leads to make drastic changes in nature in various aspects. Their effluent shows diversified impacts on the whole population. Fluoride is the element which may occur naturally in water. Fluoride concentration of approximately 1.0 mg/l in drinking water effectively reduces harmful effects on human health but intake of high concentration of fluoride beyond the tolerance level is responsible for Fluorosis. On the basis of survey, maximum population of all villages are largely effected from Fluorosis. There are 39 villages in block Bighapur. The sources of drinking water of the villages are underground wells and hand pumps and are characterized by a higher content of Fluoride. The present investigation was based on Fluoride estimation by chemical analysis. For the present study the water samples were collected randomly (February,2012 to January,2013) from the villages and were analyzed. Fluoride concentration ranged from 1.5-6.8 mg/l, whereas the permissible limit for Fluoride concentration is only 1.5 mg/l.