A field experiment was conducted during rainy-cum-winter seasons of 2013-14 and 2014-15 to study the effect of organic and inorganic sources of nutrients on grain quality, nutrient contents and uptake of pigeonpea var. ICPL-87. Farmyard manure (FYM) @ 10 t ha-1 recorded highest grain protein (22.12%), protein yield (261.6 kg ha-1), NPKS contents and their uptake. This was followed by vermicompost and then poultry manure each @ 5 t ha-1. FYM producing 68.97 q ha-1 total biomass (grain + straw) took up the maximum nutrients (92.12 kg N, 15.96 kg P, 74.70 kg K and 14.47 kg S ha-1). In case of inorganic sources, 100% RDF (N P K ) recorded maximum grain protein (21.59%) 20 60 20 and protein yield (241.3 kg ha-1). This 100% NPK level producing 60.10 q ha-1 total biomass resulted in highest percentage of NPKS contents as well as their uptake per hectare. The treatment interactions were found to be almost non-significant.